All Phenotypes Fam136a<tm1a(KOMP)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Fam136a^{tm1a(KOMP)Wtsi}
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:4944370

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fam136a^{tm1a(KOMP)Wtsi}/Fam136a^{tm1a(KOMP)Wtsi}	B6NTac;B6N-A^tm1Brd Fam136a^{tm1a(KOMP)Wtsi}/Wtsi	MGI:7579291

Allelic Composition	Fam136a^{tm1a(KOMP)Wtsi}/Fam136a^{tm1a(KOMP)Wtsi}
Genetic Background	B6NTac;B6N-A^tm1Brd Fam136a^{tm1a(KOMP)Wtsi}/Wtsi
Cell Lines	EPD0748_4_C04

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fam136a^{tm1a(KOMP)Wtsi} mutation (2 available); any Fam136a mutation (13 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hearing/vestibular/ear

increased susceptibility to age-related hearing loss ( J:338249 )

• homozygotes lose their hearing ability significantly earlier than wild-type controls (9-11 months vs 15-20 months, respectively), as determined by startle reflex-based clicker tests

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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