All Phenotypes Abl1<tm1.1Gcos> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Abl1^tm1.1Gcos
targeted mutation 1.1, Giulio Cossu
MGI:4939889

Summary

2 genotypes

Allelic Composition	Abl1^tm1.1Gcos/Abl1^tm1.1Gcos
Genetic Background	involves: 129S1/Sv * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abl1^tm1.1Gcos mutation (0 available); any Abl1 mutation (94 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

muscle

abnormal myogenesis ( J:168843 )

• MyoD-activated myogenesis in fibroblasts is not suppressed by genotoxins unlike in similarly treated wild-type cells

homeostasis/metabolism

• MyoD-activated myogenesis in fibroblasts is not suppressed by genotoxins unlike in similarly treated wild-type cells

Allelic Composition	Abl1^tm1.1Gcos/Abl1⁺
Genetic Background	involves: 129S1/Sv * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abl1^tm1.1Gcos mutation (0 available); any Abl1 mutation (94 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

muscle

abnormal myogenesis ( J:168843 )

• MyoD-activated myogenesis in fibroblasts is not suppressed by genotoxins unlike in similarly treated wild-type cells

homeostasis/metabolism

• MyoD-activated myogenesis in fibroblasts is not suppressed by genotoxins unlike in similarly treated wild-type cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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