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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Grhl1m1J
mutation 1, Jackson
MGI:4938813
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Grhl1m1J/Grhl1m1J B6.Cg-Grhl1m1J/GrsrJ MGI:4942416


Genotype
MGI:4942416
hm1
Allelic
Composition
Grhl1m1J/Grhl1m1J
Genetic
Background
B6.Cg-Grhl1m1J/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grhl1m1J mutation (1 available); any Grhl1 mutation (33 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Grhl1m1J/Grhl1m1J mouse (front) with sparse hair compared to normal sibling control (back)

integument
• ichthyotic balding is seen by 1.5 weeks of age, homozygotes are almost bald at wean age and their coats remain sparse throughout adulthood

growth/size/body
• homozygotes are notably smaller than control littermates yet are viable and fertile





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory