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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mecp2tm3.1Bird
targeted mutation 3.1, Adrian Bird
MGI:4938309
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mecp2tm3.1Bird/Mecp2tm3.1Bird involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 MGI:4938616
ot2
 		Mecp2tm3.1Bird/Y involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 MGI:4938615
ot3
 		Mecp2tm3.1Bird/Y involves: 129P2/OlaHsd * C57BL/6 MGI:5702967


Genotype
MGI:4938616
hm1
Allelic
Composition		 Mecp2tm3.1Bird/Mecp2tm3.1Bird
Genetic
Background		 involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mecp2tm3.1Bird mutation (1 available); any Mecp2 mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:168822 )
• mice are viable, fertile, and normal in size and do not display any gross physical or behavioral abnormalities




Genotype
MGI:4938615
ot2
Allelic
Composition		 Mecp2tm3.1Bird/Y
Genetic
Background		 involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mecp2tm3.1Bird mutation (1 available); any Mecp2 mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:168822 )
• mice are viable, fertile, and normal in size and do not display any gross physical or behavioral abnormalities




Genotype
MGI:5702967
ot3
Allelic
Composition		 Mecp2tm3.1Bird/Y
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mecp2tm3.1Bird mutation (1 available); any Mecp2 mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal motor capabilities/coordination/movement ( J:227401 )
• slightly increased latency to fall in hanging wire test

growth/size/body
decreased body weight ( J:227401 )
• weight gain is less than wild-type litter mates when measured collectively (Repeated Measures ANOVA), but not at single time points




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory