Phenotypes associated with this allele

• Allele Symbol: Faim2^tm1.1Jbsc
• Allele Name: targeted mutation 1.1, Joerg B Schulz
• Allele ID: MGI:4888719
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Faim2^tm1.1Jbsc/Faim2^tm1.1Jbsc	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N	MGI:4888738

Genotype
MGI:4888738

hm1

• Allelic Composition: Faim2^tm1.1Jbsc/Faim2^tm1.1Jbsc
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

increased cerebral infarct size ( J:167848 )

• 30 minutes of middle cerebral artery occlusion followed by 72 hours of reperfusion results in significantly enlarged lesion volumes

• increased numbers of apoptotic cells in lesions and in the ipsilateral hemisphere

• striatal injection of lentiviral Faim2 expression constructs 3 weeks before middle cerebral artery occlusion results in significantly reduced lesion volume

homeostasis/metabolism

increased cerebral infarct size ( J:167848 )

• 30 minutes of middle cerebral artery occlusion followed by 72 hours of reperfusion results in significantly enlarged lesion volumes

• increased numbers of apoptotic cells in lesions and in the ipsilateral hemisphere

• striatal injection of lentiviral Faim2 expression constructs 3 weeks before middle cerebral artery occlusion results in significantly reduced lesion volume