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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Atrxtm1Enl
targeted mutation 1, En Li
MGI:4888669
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Atrxtm1Enl/Atrxtm1Enl B6.129S4-Atrxtm1Enl MGI:4889107


Genotype
MGI:4889107
hm1
Allelic
Composition		 Atrxtm1Enl/Atrxtm1Enl
Genetic
Background		 B6.129S4-Atrxtm1Enl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atrxtm1Enl mutation (1 available); any Atrx mutation (78 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, incomplete penetrance ( J:168608 )
• birth rates are lower than for normal mice

behavior/neurological
behavior/neurological phenotype ( J:168608 )
N
• mice exhibit normal spatial and reference memory and normal sensitivity to painful stimulus

nervous system
reduced long-term potentiation ( J:168608 )
• in the hippocampus

growth/size/body
decreased body weight ( J:168608 )




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory