Phenotypes associated with this allele

• Allele Symbol: Lamtor1^tm1Moka
• Allele Name: targeted mutation 1, Masato Okada
• Allele ID: MGI:4888381
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lamtor1^tm1Moka/Lamtor1^tm1Moka	involves: C57BL/6	MGI:4888387

Genotype
MGI:4888387

hm1

• Allelic Composition: Lamtor1^tm1Moka/Lamtor1^tm1Moka
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:168293 )

• at the egg cylinder stage around E7

embryo

embryonic growth arrest ( J:168293 )

• at E7

abnormal extraembryonic endoderm formation ( J:168293 )

• the apical surface is expanded with accumulation of small LAP-1+ vesicles and tubular endosome-related organelles beneath the apical membrane unlike in wild-type mice

abnormal visceral endoderm morphology ( J:168293 )

• cells from the visceral endoderm of E7 embryos exhibit small lysosomal structures with amorphous substances unlike in wild-type mice

cellular

abnormal lysosome morphology ( J:168293 )

• cells from the visceral endoderm of E7 embryos exhibit small lysosomal structures with amorphous substances unlike in wild-type mice