Analysis Tools
mortality/aging
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• no mice are produced from mating heterozygotes
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Allele Symbol Allele Name Allele ID |
Hkdc1tm1a(KOMP)Wtsi targeted mutation 1a, Wellcome Trust Sanger Institute MGI:4887590 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• no mice are produced from mating heterozygotes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• 120 minutes after a glucose challenge with a bolus of labeled glucose, a reduced quantity of labelled glucose was present in tissue from heterozygous mice, especially in the small intestine, with a trend toward lower levels in the other tissues
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| N |
• mice exhibit normal insulin secretion, insulin sensitivity, gluconeogenesis and metabolic phenotype
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• in female and male mice at 28 weeks of age
• in pregnant mice at 15 days gestation
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• in female mice with lower trends in male mice
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• in female mice with lower trends in male mice
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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