Phenotypes associated with this allele
Allelic Composition |
Del(10Prmt2-Cstb)4Yah/+
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Genetic Background |
involves: 129P2/OlaHsd * BALB/c * C3H/HeH * C57BL/6 |
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(10Prmt2-Cstb)4Yah mutation
(1 available);
any
Del(10Prmt2-Cstb)4Yah mutation
(1 available)
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behavior/neurological
N |
• performance on a rotarod similar to controls
• performance on a notched bar test of hindlimb performance is similar to controls
• anxiety measured in an open field test similar to controls
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(10Prmt2-Cstb)4Yah mutation
(1 available);
any
Del(10Prmt2-Cstb)4Yah mutation
(1 available)
Tc(HSA21)1TybEmcf mutation
(3 available);
any
Tc(HSA21)1TybEmcf mutation
(4 available)
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behavior/neurological
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• slower to learn task in a Morris Maze test
• travelled further to find the hidden platform
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• little retention of learning seen during probe trials in a Morris Maze test
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• less time spent in the periphery of an open field test
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• perform poorly on a rotarod
• fall of a rotarod more rapidly and at slower speeds
• rotarod performance does not improve with practice
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• 25% more errors than controls on a notched bar test of hindlimb performance
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• investigation of a newly introduced mouse is normal
• no distinction made between mice after the later introduction of a second new mouse
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