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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pde6atvrm58
translational vision research model 58
MGI:4867884
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pde6atvrm58/Pde6atvrm58 involves: C57BL/6J MGI:5609963
ht2
 		Pde6anmf282/Pde6atvrm58 involves: A/J * C57BL/6J MGI:5609969


Genotype
MGI:5609963
hm1
Allelic
Composition		 Pde6atvrm58/Pde6atvrm58
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pde6atvrm58 mutation (1 available); any Pde6a mutation (52 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal ocular fundus morphology ( J:214072 )
• mottled, grainy fundus
• however, retina morphology is normal at 2 weeks
thin retina outer nuclear layer ( J:214072 )
• reduced to 2 to 3 nuclei thickness by 3 weeks
retina degeneration ( J:166679 , J:214072 )
• early and rapid (J:166679)




Genotype
MGI:5609969
ht2
Allelic
Composition		 Pde6anmf282/Pde6atvrm58
Genetic
Background		 involves: A/J * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pde6anmf282 mutation (1 available); any Pde6a mutation (52 available)
Pde6atvrm58 mutation (1 available); any Pde6a mutation (52 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory