Phenotypes associated with this allele

• Allele Symbol: Pdcd2^tm1Jcs
• Allele Name: targeted mutation 1, John C Schimenti
• Allele ID: MGI:4867683
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pdcd2^tm1Jcs/Pdcd2^tm1Jcs	involves: 129S4/SvJae * C57BL/6J	MGI:4867684

Genotype
MGI:4867684

hm1

• Allelic Composition: Pdcd2^tm1Jcs/Pdcd2^tm1Jcs
• Genetic Background: involves: 129S4/SvJae * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality before implantation, complete penetrance ( J:166618 )

• embryos tend to arrest before the blastocyst stage

embryo

failure of blastocyst to hatch from the zona pellucida ( J:166618 )

• 5 of 7, E3.5 embryos failed to attach and hatch in culture

embryonic growth arrest ( J:166618 )

• embryos tend to arrest before the blastocyst stage

embryonic growth retardation ( J:166618 )

• at E3.5, 5 of 7 embryos were delayed at the cleavage or morula stages

abnormal inner cell mass morphology ( J:166618 )

• the 2 embryos that did hatch from the zona pellucida failed to exhibit ICM outgrowth

growth/size/body

embryonic growth retardation ( J:166618 )

• at E3.5, 5 of 7 embryos were delayed at the cleavage or morula stages