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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ighg1tm3Cgn
targeted mutation 1, University of Cologne
MGI:4850022
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Ighg1tm3Cgn/Ighg1+ involves: 129P2/OlaHsd * BALB/c * C57BL/6 MGI:4850031


Genotype
MGI:4850031
ht1
Allelic
Composition		 Ighg1tm3Cgn/Ighg1+
Genetic
Background		 involves: 129P2/OlaHsd * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ighg1tm3Cgn mutation (0 available); any Ighg1 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal class switch recombination ( J:166887 )
• no serum IgG1a
• reduced IgG1b
decreased IgG1 level ( J:166887 )
• no serum IgG1a
• reduced IgG1b

hematopoietic system
abnormal class switch recombination ( J:166887 )
• no serum IgG1a
• reduced IgG1b
decreased IgG1 level ( J:166887 )
• no serum IgG1a
• reduced IgG1b




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory