About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ighg1tm3Cgn
targeted mutation 1, University of Cologne
MGI:4850022
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Ighg1tm3Cgn/Ighg1+ involves: 129P2/OlaHsd * BALB/c * C57BL/6 MGI:4850031


Genotype
MGI:4850031
ht1
Allelic
Composition		 Ighg1tm3Cgn/Ighg1+
Genetic
Background		 involves: 129P2/OlaHsd * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ighg1tm3Cgn mutation (0 available); any Ighg1 mutation (28 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal class switch recombination ( J:166887 )
• no serum IgG1a
• reduced IgG1b
decreased IgG1 level ( J:166887 )
• no serum IgG1a
• reduced IgG1b

hematopoietic system
abnormal class switch recombination ( J:166887 )
• no serum IgG1a
• reduced IgG1b
decreased IgG1 level ( J:166887 )
• no serum IgG1a
• reduced IgG1b




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory