All Phenotypes Klk7<tm1(KOMP)Vlcg> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Klk7^{tm1(KOMP)Vlcg}
targeted mutation 1, Velocigene
MGI:4843047

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Klk7^{tm1(KOMP)Vlcg}/Klk7^{tm1(KOMP)Vlcg}	involves: C57BL/6NTac	MGI:6160917
cx2	App^tm3.1Tcs/App^tm3.1Tcs Klk7^{tm1(KOMP)Vlcg}/Klk7^{tm1(KOMP)Vlcg}	involves: C57BL/6NTac	MGI:6160918

Allelic Composition	Klk7^{tm1(KOMP)Vlcg}/Klk7^{tm1(KOMP)Vlcg}
Genetic Background	involves: C57BL/6NTac

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klk7^{tm1(KOMP)Vlcg} mutation (1 available); any Klk7 mutation (13 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:261970 )

• normal and were fertile

Allelic Composition	App^tm3.1Tcs/App^tm3.1Tcs Klk7^{tm1(KOMP)Vlcg}/Klk7^{tm1(KOMP)Vlcg}
Genetic Background	involves: C57BL/6NTac

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
App^tm3.1Tcs mutation (2 available); any App mutation (89 available)
Klk7^{tm1(KOMP)Vlcg} mutation (1 available); any Klk7 mutation (13 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

amyloid beta deposits ( J:261970 )

• increased 5.6-fold compared with App^tm3.1Tcs homozygotes

homeostasis/metabolism

amyloid beta deposits ( J:261970 )

• increased 5.6-fold compared with App^tm3.1Tcs homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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