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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Chst15tm1Oh
targeted mutation 1, Osami Habuchi
MGI:4840254
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Chst15tm1Oh/Chst15tm1Oh involves: 129P2/OlaHsd * C57BL/6 MGI:4840257


Genotype
MGI:4840257
hm1
Allelic
Composition		 Chst15tm1Oh/Chst15tm1Oh
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chst15tm1Oh mutation (2 available); any Chst15 mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Abnormal morphology of Chst15tm1Oh/Chst15tm1Oh bone marrow-derived mast cells

reproductive system
decreased litter size ( J:165927 )
• reduced litter size in crosses between homozygotes

hematopoietic system
abnormal mast cell morphology ( J:165927 )
• bone marrow derived mast cells show only weak metachromatic staining
• higher portion of empty granules

immune system
abnormal mast cell morphology ( J:165927 )
• bone marrow derived mast cells show only weak metachromatic staining
• higher portion of empty granules




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory