All Phenotypes Fbn1<tm2.1Lysa> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Fbn1^tm2.1Lysa
targeted mutation 2.1, Lynn Y Sakai
MGI:4839071

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fbn1^tm2.1Lysa/Fbn1^tm2.1Lysa	involves: C57BL/6	MGI:4839091

Allelic Composition	Fbn1^tm2.1Lysa/Fbn1^tm2.1Lysa
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbn1^tm2.1Lysa mutation (0 available); any Fbn1 mutation (174 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:165897 )

N	• mice exhibit normal lifespan unlike mice homozygous for other Fbn1 mutations

cardiovascular system

cardiovascular system phenotype ( J:165897 )

N	• aortic elastic fiber morphology is normal

integument

integument phenotype ( J:165897 )

N	• mice exhibit normal cutaneous microfibril morphology

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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