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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sorcs1tm1.1Gndy
targeted mutation 1.1, Samuel Gandy
MGI:4836913
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Sorcs1tm1.1Gndy/Sorcs1tm1.1Gndy involves: 129 * C57BL/6 * FVB/N MGI:4836914


Genotype
MGI:4836914
hm1
Allelic
Composition		 Sorcs1tm1.1Gndy/Sorcs1tm1.1Gndy
Genetic
Background		 involves: 129 * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sorcs1tm1.1Gndy mutation (0 available); any Sorcs1 mutation (81 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
amyloid beta deposits ( J:164876 )
• increase in endogenous murine amyloid beta 40 and amyloid beta 42 levels in the brains of females

homeostasis/metabolism
amyloid beta deposits ( J:164876 )
• increase in endogenous murine amyloid beta 40 and amyloid beta 42 levels in the brains of females




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory