Phenotypes associated with this allele

• Allele Symbol: Trpv3^tm1.1Clph
• Allele Name: targeted mutation 1.1, David E Clapham
• Allele ID: MGI:4836895
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Tg(KRT14-cre)1Amc/0 Trpv3^tm1.1Clph/Trpv3^tm1.1Clph	involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * CBA * Swiss Webster	MGI:4836900

Genotype
MGI:4836900

cn1

• Allelic Composition: Tg(KRT14-cre)1Amc/0; Trpv3^tm1.1Clph/Trpv3^tm1.1Clph
• Genetic Background: involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * CBA * Swiss Webster

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

erythroderma ( J:164741 )

integument

erythroderma ( J:164741 )

waved hair ( J:164741 )

• dorsal and ventral coat fur as well as tail hair with 100% penetrance

abnormal hair follicle orientation ( J:164741 )

• gently curved and pointed in different directions with variable angles

curly vibrissae ( J:164741 )

• with 100% penetrance

abnormal epidermis stratum corneum morphology ( J:164741 )

abnormal corneocyte envelope morphology ( J:164741 )

• The density of the cornified cell envelope is only 15-18% of wild-type

dry skin ( J:164741 )

scaly skin ( J:164741 )