All Phenotypes Nedd4<tm3.1Bros> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Nedd4^tm3.1Bros
targeted mutation 3.1, Nils Brose
MGI:4836405

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Nedd4^tm3.1Bros/Nedd4^tm3.1Bros Neurod6^tm1(cre)Kan/Neurod6⁺	involves: 129 * C57BL/6 * C57BL/6N * SJL	MGI:4836485

Allelic Composition	Nedd4^tm3.1Bros/Nedd4^tm3.1Bros Neurod6^tm1(cre)Kan/Neurod6⁺
Genetic Background	involves: 129 * C57BL/6 * C57BL/6N * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nedd4^tm3.1Bros mutation (0 available); any Nedd4 mutation (116 available)
Neurod6^tm1(cre)Kan mutation (0 available); any Neurod6 mutation (17 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:164745 )

N	• cerebellum size is normal

abnormal cerebral hemisphere morphology ( J:164745 )

• small

thin cerebral cortex ( J:164745 )

abnormal dendrite morphology ( J:164745 )

• dendrite extent and branching on CA1 region neurons are reduced compared to in wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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