All Phenotypes Kcnn2<bc-6J> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Kcnn2^bc-6J
bouncy 6 Jackson
MGI:4834267

Summary

2 genotypes

Allelic Composition	Kcnn2^bc-6J/Kcnn2^bc-6J
Genetic Background	C57BL/6J-Kcnn2^bc-6J/GrsrJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnn2^bc-6J mutation (1 available); any Kcnn2 mutation (43 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

male infertility ( J:215011 )

• males are usually sterile, although in vitro fertilization can succeed using homozygous sperm

behavior/neurological

tremors ( J:215011 )

• homozygotes have a jittery trembling movement most noticeable at 3 weeks of age and less apparent as the mice age

abnormal gait ( J:215011 )

hearing/vestibular/ear

hearing/vestibular/ear phenotype ( J:215011 )

N	• ABR assessment of 3 homozygotes at 5 months of age found no hearing deficit

vision/eye

vision/eye phenotype ( J:215011 )

N	• ophthalmoscopic examination of 3 homozygotes at 5 months of age found no ocular abnormalities

Allelic Composition	Kcnn2^bc-6J/Kcnn2^bc-6J
Genetic Background	involves: C57BL/6J * CAST/EiJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnn2^bc-6J mutation (1 available); any Kcnn2 mutation (43 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• fewer than 19% homozygotes are generated in the F2 population from intercrosses of F1 heterozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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