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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Thy1-cre/ERT2,-EYFP)HGfng
transgene insertion H, Guoping Feng
MGI:4830789
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Gpx4tm1.1Qra/Gpx4tm1.1Qra
Tg(Thy1-cre/ERT2,-EYFP)HGfng/0 		involves: 129S6/SvEvTac * C57BL/6J * CBA MGI:8394384


Genotype
MGI:8394384
cn1
Allelic
Composition		 Gpx4tm1.1Qra/Gpx4tm1.1Qra
Tg(Thy1-cre/ERT2,-EYFP)HGfng/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6J * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gpx4tm1.1Qra mutation (1 available); any Gpx4 mutation (80 available)
Tg(Thy1-cre/ERT2,-EYFP)HGfng mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:389717 )
• mice typically die within 2 weeks of induction with tamoxifen

behavior/neurological
impaired coordination ( J:389717 )
• on a vitamin B2-deficient diet, tamoxifen-treated mice show accelerated motor decline, showing reduced time to fall off the rotarod and in the hangtime test than tamoxifen-treated mice fed a chow diet




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
07/14/2026
MGI 6.24 		The Jackson Laboratory