All Phenotypes Esr1<tm1.1Pws> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Esr1^tm1.1Pws
targeted mutation 1.1, Philip W Shaul
MGI:4829939

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Esr1^tm1.1Pws/Esr1^tm1.1Pws	involves: C57BL/6 * CBA	MGI:4829961

Allelic Composition	Esr1^tm1.1Pws/Esr1^tm1.1Pws
Genetic Background	involves: C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Esr1^tm1.1Pws mutation (0 available); any Esr1 mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

abnormal reproductive system morphology ( J:163783 )

• authors state that mice exhibit similar reproductive phenotypes observed in Esr1^tm1.1Mma homozygotes

cardiovascular system

abnormal vascular wound healing ( J:163783 )

• following arterial denudation, mice exhibit decreased estrogen and estrogen-dendrimer conjugate (EDC)-stimulated reendothelialization compared with similarly treated wild-type mice

homeostasis/metabolism

abnormal vascular wound healing ( J:163783 )

• following arterial denudation, mice exhibit decreased estrogen and estrogen-dendrimer conjugate (EDC)-stimulated reendothelialization compared with similarly treated wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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