All Phenotypes Mir451a<tm1.2Doca> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mir451a^tm1.2Doca
targeted mutation 1.2, Donal O'Carroll
MGI:4829620

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mir451a^tm1.2Doca/Mir451a^tm1.2Doca	involves: 129P2/OlaHsd * 129S4/SvJaeSor * BALB/cJ	MGI:4829627

Allelic Composition	Mir451a^tm1.2Doca/Mir451a^tm1.2Doca
Genetic Background	involves: 129P2/OlaHsd * 129S4/SvJaeSor * BALB/cJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir451a^tm1.2Doca mutation (1 available); any Mir451a mutation (5 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

abnormal hematopoietic system morphology/development ( J:163418 )

• authors state that mice exhibit a largely indistinguishable phenotype from Mir144/Mir451^tm1.2Doca homozygotes

enlarged spleen ( J:163418 )

increased erythroid progenitor cell number ( J:163418 )

• in the spleen

decreased erythrocyte cell number ( J:163418 )

decreased hematocrit ( J:163418 )

increased red blood cell distribution width ( J:163418 )

immune system

enlarged spleen ( J:163418 )

growth/size/body

enlarged spleen ( J:163418 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24