Phenotypes associated with this allele

• Allele Symbol: Cacng2^tm1.1Suto
• Allele Name: targeted mutation 1.1, Susumu Tomita
• Allele ID: MGI:4822223
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cacng2^tm1.1Suto/Cacng2^tm1.1Suto	Not Specified	MGI:4822239

Genotype
MGI:4822239

hm1

• Allelic Composition: Cacng2^tm1.1Suto/Cacng2^tm1.1Suto
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:163184 )

N • paired-pulse facilitation is normal

abnormal AMPA-mediated synaptic currents ( J:163184 )

• the ratio of AMPA receptor to the NMDA receptor components of the excitatory postsynaptic currents is increased compared to wild-type mice

increased miniature excitatory postsynaptic current amplitude ( J:163184 )

• the amplitude of miniature excitatory postsynaptic currents (mEPSCs) is increased compared to in wild-type mice

• however, mEPSCs frequency is normal