All Phenotypes App<tm3.2Umu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

App^tm3.2Umu
targeted mutation 3.2, Ulrike Muller
MGI:4822178

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	App^tm3.2Umu/App^tm2Cwe	involves: 129P2/OlaHsd * BALB/cJ * C57BL/6N	MGI:4822179

Allelic Composition	App^tm3.2Umu/App^tm2Cwe
Genetic Background	involves: 129P2/OlaHsd * BALB/cJ * C57BL/6N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
App^tm2Cwe mutation (0 available); any App mutation (89 available)
App^tm3.2Umu mutation (0 available); any App mutation (89 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased grip strength ( J:163059 )

• displayed a pronounced and significant difference in grip strength compared to wild-type mice

growth/size/body

decreased body weight ( J:163059 )

• body weight is reduced by about 10.6%

nervous system

decreased brain weight ( J:163059 )

• wet brain weight is reduced

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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