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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Col4a2ENU4003
ENU mutation 4003
MGI:4822172
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Col4a2ENU4003/Col4a2ENU4003 C3.D2-Col4a2ENU4003 MGI:4822374
ht2
 		Col4a2ENU4003/Col4a2+ C3.D2-Col4a2ENU4003 MGI:4822255


Genotype
MGI:4822374
hm1
Allelic
Composition		 Col4a2ENU4003/Col4a2ENU4003
Genetic
Background		 C3.D2-Col4a2ENU4003
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col4a2ENU4003 mutation (1 available); any Col4a2 mutation (74 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
lethality throughout fetal growth and development, complete penetrance ( J:163225 )
• reduced numbers of embryos consistent with death of all homozygotes
• no homozygotes at birth




Genotype
MGI:4822255
ht2
Allelic
Composition		 Col4a2ENU4003/Col4a2+
Genetic
Background		 C3.D2-Col4a2ENU4003
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col4a2ENU4003 mutation (1 available); any Col4a2 mutation (74 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal lens morphology ( J:163225 )
• total lens opacity

hematopoietic system

nervous system
abnormal brain morphology ( J:163225 )
• abnormal brain anatomy in some but not all mice

cardiovascular system
hemorrhage ( J:163225 )
• intraorbital hemorrhage




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory