Phenotypes associated with this allele

• Allele Symbol: Agap1^{tm1a(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4820274
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Agap1^tm1a(EUCOMM)Wtsi/Agap1^tm1a(EUCOMM)Wtsi	C57BL/6N-Agap1^tm1a(EUCOMM)Wtsi/Wtsi	MGI:5630837

Genotype
MGI:5630837

hm1

• Allelic Composition: Agap1^{tm1a(EUCOMM)Wtsi}/Agap1^{tm1a(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Agap1^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0615_1_B03

Data Sources

IMPC Data for Agap1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

absent pinna reflex ( J:211773 )

IMPC - WTSI

craniofacial

abnormal cranium morphology ( J:211773 )

♀

IMPC - WTSI

abnormal tooth morphology ( J:211773 )

IMPC - WTSI

abnormal snout morphology ( J:211773 )

♀

IMPC - WTSI

growth/size/body

abnormal tooth morphology ( J:211773 )

IMPC - WTSI

abnormal snout morphology ( J:211773 )

♀

IMPC - WTSI

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - WTSI

homeostasis/metabolism

increased circulating potassium level ( J:211773 )

♀

IMPC - WTSI

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - WTSI

integument

abnormal skin coloration ( J:211773 )

IMPC - WTSI

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - WTSI

skeleton

abnormal cranium morphology ( J:211773 )

♀

IMPC - WTSI

abnormal tooth morphology ( J:211773 )

IMPC - WTSI

vision/eye

abnormal iris morphology ( J:211773 )

IMPC - WTSI

abnormal cornea morphology ( J:211773 )

♂

IMPC - WTSI

cornea opacity ( J:211773 )

♂

IMPC - WTSI

abnormal lens morphology ( J:211773 )

♀

IMPC - WTSI

fused cornea and lens ( J:211773 )

♂

IMPC - WTSI

cataract ( J:211773 )

♀

IMPC - WTSI

persistence of hyaloid vascular system ( J:211773 )

IMPC - WTSI