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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cd4sesh
seshat
MGI:4819228
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cd4sesh/Cd4sesh C57BL/6JAnu-Cd4sesh/AnuApb MGI:4819229


Genotype
MGI:4819229
hm1
Allelic
Composition		 Cd4sesh/Cd4sesh
Genetic
Background		 C57BL/6JAnu-Cd4sesh/AnuApb
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd4sesh mutation (2 available); any Cd4 mutation (85 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal double-positive T cell morphology ( J:104190 )
• reduced CD4 expression on T cells
decreased T cell number ( J:104190 )
• in the periphery
abnormal CD4-positive, alpha beta T cell morphology ( J:104190 )
• reduced CD4 expression on T cells

immune system
abnormal double-positive T cell morphology ( J:104190 )
• reduced CD4 expression on T cells
decreased T cell number ( J:104190 )
• in the periphery
abnormal CD4-positive, alpha beta T cell morphology ( J:104190 )
• reduced CD4 expression on T cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory