All Phenotypes Tg(Prnp-APP)#Hmor MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Prnp-APP)#Hmor
transgene insertion, Hiroshi Mori
MGI:4818979

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Prnp-APP)#Hmor/0	B6.Cg-Tg(Prnp-APP)#Hmor	MGI:4818992

Allelic Composition	Tg(Prnp-APP)#Hmor/0
Genetic Background	B6.Cg-Tg(Prnp-APP)#Hmor

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:159623 )

N	• no amyloid plaques are observed unlike in Tg(APPSWE)2576Kha mice • mice do not exhibit neuronal loss unlike Tg(Prnp-APP*)1Hmor mice

astrocytosis ( J:159623 )

• few at 24 months

reduced long-term potentiation ( J:159623 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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