All Phenotypes Pparg<tm1.2Auw> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pparg^tm1.2Auw
targeted mutation 1.2, Johan Auwerx
MGI:4818655

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pparg^tm1.2Auw/Pparg^tm1.2Auw	B6.Cg-Pparg^tm1.2Auw	MGI:4818659

Allelic Composition	Pparg^tm1.2Auw/Pparg^tm1.2Auw
Genetic Background	B6.Cg-Pparg^tm1.2Auw

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pparg^tm1.2Auw mutation (0 available); any Pparg mutation (39 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:161746 )

• a significant decrease in life span

• were not lipodystrophic or insulin resistant, unlike mice homozygous for Pparg^tm1Auw

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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