Phenotypes associated with this allele

• Allele Symbol: Tg(Ttr-Retn)1Laz
• Allele Name: transgene insertion 1, Mitchell A Lazar
• Allele ID: MGI:4462407
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Ttr-Retn)1Laz/?	involves: C57BL/6 * SJL	MGI:4462408

Genotype
MGI:4462408

tg1

• Allelic Composition: Tg(Ttr-Retn)1Laz/?
• Genetic Background: involves: C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:91890 )

N • body weight, body fat composition, insulin and leptin levels are all similar to control

increased circulating glucose level ( J:91890 )

• increased hepatic glucose production in hyperinsulinemic state

hyperglycemia ( J:91890 )

• fasting mice exhibit modest hyperglycemia, however, glucose levels between mutant and control are similar for ad libitum feeding

impaired glucose tolerance ( J:91890 )