All Phenotypes Ago2<tm2Ghan> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ago2^tm2Ghan
targeted mutation 2, Greggory J Hannon
MGI:4462370

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Ago2^Gt(XE344)Byg/Ago2^tm2Ghan	involves: 129P2/OlaHsd	MGI:4462373

Allelic Composition	Ago2^Gt(XE344)Byg/Ago2^tm2Ghan
Genetic Background	involves: 129P2/OlaHsd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ago2^Gt(XE344)Byg mutation (1 available); any Ago2 mutation (54 available)
Ago2^tm2Ghan mutation (0 available); any Ago2 mutation (54 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

placental labyrinth hypoplasia ( J:161968 )

• thin

small placenta ( J:161968 )

• mice exhibit a hypotrophic placenta compared with wild-type mice

• however, the giant trophoblast cell and spongiform layers are normal

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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