Analysis Tools|
Allele Symbol Allele Name Allele ID |
Vangl2Lp-2J loop tail 2 Jackson MGI:4462051 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• fewer than 50% of offspring from heterozygous intercrosses are heterozygotes
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• some newborns with severe spina bifida die shortly after birth
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• a short, curled tail is the most common phenotype seen for this mutation with incomplete penetrance
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• observed to varying degrees of severity in some, but not all, affected mice and some with mild spina bifida have lived to adulthood and reproduced
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• observed to varying degrees of severity in some, but not all, affected mice and some with mild spina bifida have lived to adulthood and reproduced
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• some heterozygotes have closed vaginas
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| N |
• no abnormal head movement
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| N |
• auditory brainstem response is normal in 2 female and 2 male heterozygotes
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/30/2025 MGI 6.24 |
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