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Allele Symbol Allele Name Allele ID |
Tg(LRRK2*G2019S)1Mjfa transgene insertion 1, Matthew Farrer MGI:4460658 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice are viable
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| N |
• mice exhibit normal gross behavior
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| N |
• mice are normal in size
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• primary neurons exhibit reduced neuron outgrowth and branching compared with control neurons
• however, indolocarbazole-treatment partially rescues outgrowth
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• primary neurons exhibit reduced neuron outgrowth and branching compared with control neurons
• however, indolocarbazole-treatment partially rescues outgrowth
|
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• primary neurons exhibit reduced neuron outgrowth and branching compared with control neurons
• however, indolocarbazole-treatment partially rescues outgrowth
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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