About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fshrtm1Hht
targeted mutation 1, Ilpo Huhtaniemi
MGI:4456197
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fshrtm1Hht/Fshrtm1Hht involves: 129S7/SvEvBrd MGI:4456207
ht2
 		Fshrtm1Hht/Fshr+ involves: 129S7/SvEvBrd MGI:4456206


Genotype
MGI:4456207
hm1
Allelic
Composition		 Fshrtm1Hht/Fshrtm1Hht
Genetic
Background		 involves: 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fshrtm1Hht mutation (0 available); any Fshr mutation (49 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
ovary hemorrhage ( J:160015 )
• abundant hemorrhagic cysts in ovaries from the age of 2.5 months onwards
• hemorrhagic cysts in 50% (8/16) of the mice at 2-3 months of age
• hemorrhagic cysts in 48% (14/29) of the mice at 6-8 months of age
• hemorrhagic cysts in 38% (6/16) of the mice at 11-13 months of age

endocrine/exocrine glands
ovary hemorrhage ( J:160015 )
• abundant hemorrhagic cysts in ovaries from the age of 2.5 months onwards
• hemorrhagic cysts in 50% (8/16) of the mice at 2-3 months of age
• hemorrhagic cysts in 48% (14/29) of the mice at 6-8 months of age
• hemorrhagic cysts in 38% (6/16) of the mice at 11-13 months of age

cardiovascular system
ovary hemorrhage ( J:160015 )
• abundant hemorrhagic cysts in ovaries from the age of 2.5 months onwards
• hemorrhagic cysts in 50% (8/16) of the mice at 2-3 months of age
• hemorrhagic cysts in 48% (14/29) of the mice at 6-8 months of age
• hemorrhagic cysts in 38% (6/16) of the mice at 11-13 months of age




Genotype
MGI:4456206
ht2
Allelic
Composition		 Fshrtm1Hht/Fshr+
Genetic
Background		 involves: 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fshrtm1Hht mutation (0 available); any Fshr mutation (49 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
ovary hemorrhage ( J:160015 )
• abundant hemorrhagic cysts in ovaries from the age of 2.5 months onwards
• hemorrhagic cysts in 25% (2/8) of the mice at 2-3 months of age
• hemorrhagic cysts in 29% (10/35) of the mice at 6-8 months of age
• hemorrhagic cysts in 38% (6/16) of the mice at 11-13 months of age

endocrine/exocrine glands
ovary hemorrhage ( J:160015 )
• abundant hemorrhagic cysts in ovaries from the age of 2.5 months onwards
• hemorrhagic cysts in 25% (2/8) of the mice at 2-3 months of age
• hemorrhagic cysts in 29% (10/35) of the mice at 6-8 months of age
• hemorrhagic cysts in 38% (6/16) of the mice at 11-13 months of age

cardiovascular system
ovary hemorrhage ( J:160015 )
• abundant hemorrhagic cysts in ovaries from the age of 2.5 months onwards
• hemorrhagic cysts in 25% (2/8) of the mice at 2-3 months of age
• hemorrhagic cysts in 29% (10/35) of the mice at 6-8 months of age
• hemorrhagic cysts in 38% (6/16) of the mice at 11-13 months of age




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory