Phenotypes associated with this allele

• Allele Symbol: Tg(Krt14-Bmp4)#Jake
• Allele Name: transgene insertion, John A Kessler
• Allele ID: MGI:4455042
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Tg(Krt14-Bmp4)#Jake/0 Tg(Krt14-Nog)#Jake/0	involves: BALB/c * C57BL/6 * FVB	MGI:4455048
tg2	Tg(Krt14-Bmp4)#Jake/0	involves: BALB/c * C57BL/6	MGI:4455047

Genotype
MGI:4455048

cx1

• Allelic Composition: Tg(Krt14-Bmp4)#Jake/0; Tg(Krt14-Nog)#Jake/0
• Genetic Background: involves: BALB/c * C57BL/6 * FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

abnormal upper incisor morphology ( J:156471 )

• grooves on the labial surface of maxillary incisors that are caused by loss of enamel

abnormal enamel morphology ( J:156471 )

• grooves on incisors result from a localized reduction of enamel on the labial surface

limbs/digits/tail

limbs/digits/tail phenotype ( J:78767 )

N • normal number and flexion of digits

interdigital webbing ( J:78767 )

• on the hindlimb, only a small web between digits II and III is seen unlike in Tg(Krt14-Nog)#Jake single transgenics

craniofacial

abnormal upper incisor morphology ( J:156471 )

• grooves on the labial surface of maxillary incisors that are caused by loss of enamel

abnormal enamel morphology ( J:156471 )

• grooves on incisors result from a localized reduction of enamel on the labial surface

growth/size/body

abnormal upper incisor morphology ( J:156471 )

• grooves on the labial surface of maxillary incisors that are caused by loss of enamel

abnormal enamel morphology ( J:156471 )

• grooves on incisors result from a localized reduction of enamel on the labial surface

Genotype
MGI:4455047

tg2

• Allelic Composition: Tg(Krt14-Bmp4)#Jake/0
• Genetic Background: involves: BALB/c * C57BL/6

limbs/digits/tail

limbs/digits/tail phenotype ( J:78767 )

N • do not display an overt limb phenotype