Analysis Tools
adipose tissue
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• in the subscapular brown adipose fat pad when fed a high fat diet
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• after 14 weeks of age when fed a high fat diet
• 59% less at 63 weeks when fed a high fat diet
• after 28 week weeks of age when fed standard chow
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• when fed a high fat diet, fat cells exhibit less cell size uniformity compared to in similarly treated wild-type mice
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• with unilocular deposition when fed a high fat diet
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• leukocyte infiltration when mice are fed a high fat diet
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• when fed a high fat diet
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• when fed a high fat diet
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• when fed a high fat diet
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• >30% less glucose uptake in WAT when fed a high fat diet
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homeostasis/metabolism
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• when fed a high fat diet
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• when fed a high fat diet, mice exhibit altered insulin sensitivity in the liver, muscle, and white adipose tissues compared with similarly treated wild-type mice
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• moderately when fed a high fat diet
• in a glucose tolerance test at week 22 when fed a high fat diet
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• by week 18 when fed a high fat diet
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• when fed a high fat diet
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• when fed a high fat diet
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growth/size/body
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• as a percentage of body weight when fed a high fat diet
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• when fed a high fat diet
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muscle
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• unlike patients with FPLD2, mice do not exhibit robust skeletal muscle hypertrophy
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• 25% less glucose uptake in muscle when fed a high fat diet
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cellular
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• >30% less glucose uptake in WAT when fed a high fat diet
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• 25% less glucose uptake in muscle when fed a high fat diet
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Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| familial partial lipodystrophy | DOID:0050440 |
OMIM:PS151660 |
J:149858 | |
