Analysis Tools
immune system
| N |
• in contrast to expectations, EAE is inducible in the homozygous mice through immunization with MOG/CFA and mice developed disease similar to wild-type controls
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Allele Symbol Allele Name Allele ID |
Il22tm1Jcrd targeted mutation 1, Jean-Christophe Renauld MGI:4453827 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• in contrast to expectations, EAE is inducible in the homozygous mice through immunization with MOG/CFA and mice developed disease similar to wild-type controls
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• in the skin of IMQ-treated mice
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• mice are partial protected from IMQ (Aldara)-induced psoriasis with decreased ear swelling and numbers of neutrophils in the skin compared with wild-type mice
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• in the skin of IMQ-treated mice
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• in the skin of IMQ-treated mice
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• before P9
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• severe
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• severe
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• severe
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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