Phenotypes associated with this allele

• Allele Symbol: Pgap2^{tm1a(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4453763
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Pgap2^clpex/Pgap2^tm1a(EUCOMM)Wtsi	involves: A/J * C57BL/6N	MGI:6342273

Genotype
MGI:6342273

ht1

• Allelic Composition: Pgap2^clpex/Pgap2^{tm1a(EUCOMM)Wtsi}
• Genetic Background: involves: A/J * C57BL/6N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

myocardium hypoplasia ( J:277316 )

• reduced thickness of myocardium at age E13.5

thin interventricular septum ( J:277316 )

• underdeveloped at age E13.5

heart valve hypoplasia ( J:277316 )

• underdeveloped at age E13.5

pericardial effusion ( J:277316 )

• at age E13.5

craniofacial

bilateral cleft upper lip ( J:277316 )

• bilateral cleft lip at age E13.5

embryo

abnormal neural tube morphology ( J:277316 )

• at age E13.5

growth/size/body

bilateral cleft upper lip ( J:277316 )

• bilateral cleft lip at age E13.5

homeostasis/metabolism

pericardial effusion ( J:277316 )

• at age E13.5

edema ( J:277316 )

• at age E13.5

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:277316 )

• by age E13.5-14.5

muscle

myocardium hypoplasia ( J:277316 )

• reduced thickness of myocardium at age E13.5

nervous system

abnormal neural tube morphology ( J:277316 )

• at age E13.5

vision/eye

microphthalmia ( J:277316 )

• at age E13.5