Phenotypes associated with this allele

• Allele Symbol: Trip10^tm1Sejc
• Allele Name: targeted mutation 1, Seth J Corey
• Allele ID: MGI:4453577
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Trip10^tm1Sejc/Trip10^tm1Sejc	involves: 129S1/Sv * 129X1/SvJ * ICR	MGI:4453860

Genotype
MGI:4453860

hm1

• Allelic Composition: Trip10^tm1Sejc/Trip10^tm1Sejc
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * ICR

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased adipocyte glucose uptake ( J:159952 )

• insulin-stimulated glucose uptake is increased compared to in wild-type cells

homeostasis/metabolism

decreased circulating glucose level ( J:159952 )

• 20 minutes after glucose challenge, mice exhibit reduced blood glucose levels compared with similarly treated wild-type mice

• fasting mice exhibit decreased glucose serum levels compared with wild-type mice

• however, post-peak serum glucose levels during glucose challenge are normal

cellular

increased adipocyte glucose uptake ( J:159952 )

• insulin-stimulated glucose uptake is increased compared to in wild-type cells