All Phenotypes Sptb<m1Jus> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Sptb^m1Jus
mutation 1, Monica J Justice
MGI:4452390

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sptb^m1Jus/Sptb^m1Jus	involves: 129S6/SvEvTac * C57BL/6	MGI:4452395

Allelic Composition	Sptb^m1Jus/Sptb^m1Jus
Genetic Background	involves: 129S6/SvEvTac * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sptb^m1Jus mutation (1 available); any Sptb mutation (86 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

enlarged heart ( J:159750 )

enlarged kidney ( J:159750 )

enlarged liver ( J:159750 )

enlarged spleen ( J:159750 )

hematopoietic system

enlarged spleen ( J:159750 )

anemia ( J:159750 )

abnormal erythrocyte morphology ( J:159750 )

• mice exhibit abnormal red blood cell morphology including spherocytes and acanthocytes unlike in wild-type mice

acanthocytosis ( J:159750 )

spherocytosis ( J:159750 )

hemolysis ( J:159750 )

• mice exhibit hemolysis unlike wild-type mice

cardiovascular system

enlarged heart ( J:159750 )

liver/biliary system

enlarged liver ( J:159750 )

renal/urinary system

enlarged kidney ( J:159750 )

immune system

enlarged spleen ( J:159750 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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