Phenotypes associated with this allele

• Allele Symbol: Rala^{tm1a(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4451975
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rala^tm1a(EUCOMM)Wtsi/Rala^tm1a(EUCOMM)Wtsi	C57BL/6N-Rala^tm1a(EUCOMM)Wtsi/Wtsi	MGI:5700971

Genotype
MGI:5700971

hm1

• Allelic Composition: Rala^{tm1a(EUCOMM)Wtsi}/Rala^{tm1a(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Rala^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0532_3_H04

Data Sources

IMPC Data for Rala

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

retroesophageal right subclavian artery ( J:239583 )

DMDD

anastomosis between internal carotid artery and basilar artery ( J:239583 )

DMDD

absent segment of posterior cerebral artery ( J:239583 )

DMDD

abnormal vertebral artery morphology ( J:239583 )

DMDD

abnormal vertebral artery topology ( J:239583 )

DMDD

abnormal vitelline vein topology ( J:239583 )

DMDD

abnormal ductus venosus morphology ( J:239583 )

DMDD

abnormal ductus venosus valve morphology ( J:239583 )

DMDD

muscular ventricular septal defect ( J:239583 )

DMDD

intraventricular hemorrhage ( J:239583 )

DMDD

spinal hemorrhage ( J:239583 )

DMDD

embryo

abnormal vitelline vein topology ( J:239583 )

DMDD

abnormal Mullerian duct morphology ( J:239583 )

DMDD

abnormal Wolffian duct morphology ( J:239583 )

DMDD

embryo cyst ( J:239583 )

DMDD

endocrine/exocrine glands

abnormal cystic duct morphology ( J:239583 )

DMDD

multiple persisting craniopharyngeal ducts ( J:239583 )

DMDD

growth/size/body

embryo cyst ( J:239583 )

DMDD

hearing/vestibular/ear

abnormal inner ear morphology ( J:239583 )

DMDD

immune system

blood in lymph vessels ( J:239583 )

DMDD

limbs/digits/tail

abnormal humerus morphology ( J:239583 )

DMDD

liver/biliary system

abnormal cystic duct morphology ( J:239583 )

DMDD

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - WTSI

muscle

abnormal eye muscle morphology ( J:239583 )

DMDD

neoplasm

increased hemangioma incidence ( J:239583 )

DMDD

nervous system

intraventricular hemorrhage ( J:239583 )

DMDD

spinal hemorrhage ( J:239583 )

DMDD

small superior cervical ganglion ( J:239583 )

DMDD

reduced sympathetic cervical ganglion size ( J:239583 )

DMDD

abnormal brain morphology ( J:239583 )

DMDD

anastomosis between internal carotid artery and basilar artery ( J:239583 )

DMDD

absent segment of posterior cerebral artery ( J:239583 )

DMDD

enlarged brain ventricles ( J:239583 )

DMDD

abnormal forebrain morphology ( J:239583 )

DMDD

multiple persisting craniopharyngeal ducts ( J:239583 )

DMDD

abnormal third ventricle morphology ( J:239583 )

DMDD

abnormal olfactory bulb morphology ( J:239583 )

DMDD

abnormal hindbrain morphology ( J:239583 )

DMDD

exencephaly ( J:239583 )

DMDD

abnormal spinal cord central canal morphology ( J:239583 )

DMDD

renal/urinary system

abnormal ureter morphology ( J:239583 )

DMDD

skeleton

abnormal humerus morphology ( J:239583 )

DMDD

fusion of vertebral arches ( J:239583 )

DMDD

vision/eye

abnormal eye muscle morphology ( J:239583 )

DMDD

abnormal lens morphology ( J:239583 )

DMDD

abnormal optic stalk morphology ( J:239583 )

DMDD

coloboma ( J:239583 )

DMDD

retrolental blood ( J:239583 )

DMDD