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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm1.1(CAG-Trp53*,-EGFP)Medz
targeted mutation 1.1, Ruslan Medzhltov
MGI:4443071
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gt(ROSA)26Sortm1.1(CAG-Trp53*,-EGFP)Medz/Gt(ROSA)26Sortm1.1(CAG-Trp53*,-EGFP)Medz involves: C57BL/6 MGI:4443112


Genotype
MGI:4443112
hm1
Allelic
Composition		 Gt(ROSA)26Sortm1.1(CAG-Trp53*,-EGFP)Medz/Gt(ROSA)26Sortm1.1(CAG-Trp53*,-EGFP)Medz
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1.1(CAG-Trp53*,-EGFP)Medz mutation (0 available); any Gt(ROSA)26Sor mutation (1046 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased thymocyte apoptosis ( J:158953 )
• in response to irradiation

immune system
decreased thymocyte apoptosis ( J:158953 )
• in response to irradiation

cellular
decreased thymocyte apoptosis ( J:158953 )
• in response to irradiation

endocrine/exocrine glands
decreased thymocyte apoptosis ( J:158953 )
• in response to irradiation




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory