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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Muc2m2Btlr
mutation 2, Bruce Beutler
MGI:4442897
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ot1
 		Muc2m2Btlr/? C57BL/6J-Muc2m2Btlr MGI:4442898


Genotype
MGI:4442898
ot1
Allelic
Composition		 Muc2m2Btlr/?
Genetic
Background		 C57BL/6J-Muc2m2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Muc2m2Btlr mutation (1 available); any Muc2 mutation (86 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
increased susceptibility to induced colitis ( J:159359 )
• on days 6 and 7 of exposure to 1% dextran sulfate sodium (DSS) in their drinking water, mice with this mutation exhibit more severe bleeding and weight loss than wild-type C57BL/6J mice

immune system
increased susceptibility to induced colitis ( J:159359 )
• on days 6 and 7 of exposure to 1% dextran sulfate sodium (DSS) in their drinking water, mice with this mutation exhibit more severe bleeding and weight loss than wild-type C57BL/6J mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory