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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Nckipsdtm1.2Toft
targeted mutation 1.2, Tomoko Fukumi-Tominaga
MGI:4442818
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Nckipsdtm1.2Toft/Nckipsdtm1.2Toft involves: 129S2/SvPas * C57BL/6 * FVB/N MGI:4442826


Genotype
MGI:4442826
hm1
Allelic
Composition
Nckipsdtm1.2Toft/Nckipsdtm1.2Toft
Genetic
Background
involves: 129S2/SvPas * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nckipsdtm1.2Toft mutation (0 available); any Nckipsd mutation (27 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• mouse embryonic fibroblasts are longer and thinner with more stress fibers than wild-type cells
• mouse embryonic fibroblasts exhibit impaired cell adhesion compared with wild-type cells
• serum-starved mouse embryonic stem cells exhibit reduced motility compared with wild-type cells

growth/size/body
N
• mice exhibit normal growth

reproductive system
N
• mice exhibit normal fertilization





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory