Analysis Tools
homeostasis/metabolism
| N |
• when fed a high-fat diet, mice exhibit resistance to diet induced hyperinsulinemia and insulin resistance
(J:158295)
• mice exhibit normal response to renal ischemia-reperfusion injury
(J:204961)
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• when fed a high-fat diet
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• in fasted mice fed a high-fat diet
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• whether fed chow or a high-fat diet
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• whether fed chow or a high-fat diet
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• whether fed chow or a high-fat diet, mice exhibit increased insulin sensitivity compared with similarly treated wild-type mice
• when fed a high-fat diet, mice exhibit increased glucose infusion rate suggesting improved skeletal muscle insulin sensitivity compared with similarly treated wild-type mice
• whether fed chow or a high-fat diet, mice exhibit reduced hepatic glucose output and greater insulin-induced suppression of hepatic glucose production indicating increased hepatic insulin sensitivity compared with similarly treated wild-type mice
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• when fed a high-fat diet, mice exhibit decreased hepatic levels of triglyceride, diglyceride, and ceramide compared with wild-type mice
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• when fed a high-fat diet
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liver/biliary system
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• when fed a high-fat diet
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• when fed a high-fat diet, mice exhibit decreased hepatic levels of triglyceride, diglyceride, and ceramide compared with wild-type mice
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• hepatocytes exhibit increased fatty acid synthesis and reduced fatty acid oxidation compared with wild-type cells
• however, insulin sensitivity of hepatocytes is normal
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growth/size/body
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• whether fed chow or a high-fat diet
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• when fed a high-fat diet
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adipose tissue
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• whether fed chow or a high-fat diet
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behavior/neurological
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• whether fed chow or a high-fat diet
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immune system
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• whether fed chow or a high-fat diet
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renal/urinary system
| N |
• mice exhibit normal response to renal ischemia-reperfusion injury
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