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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(RNU6-EGFP,-RNAi:Dpp7)#Bhub
transgene insertion, Brigitte T Huber
MGI:4438942
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Tg(Neurog3-cre)C1Able/0
Tg(RNU6-EGFP,-RNAi:Dpp7)#Bhub/0
involves: 129 * C57BL/6 * CD-1 MGI:4438946


Genotype
MGI:4438946
cn1
Allelic
Composition
Tg(Neurog3-cre)C1Able/0
Tg(RNU6-EGFP,-RNAi:Dpp7)#Bhub/0
Genetic
Background
involves: 129 * C57BL/6 * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Neurog3-cre)C1Able mutation (2 available)
Tg(RNU6-EGFP,-RNAi:Dpp7)#Bhub mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• whether fed a low-fat or high-fat diet, serum glucose levels are higher than in wild-type mice especially in male mice
• as early as 4 months of age whether fed a low-fat or high-fat diet
• baseline and after glucose challenge whether fed a low-fat or high-fat diet
• as early as 4 months of age whether fed a low-fat or high-fat diet
• whether fed a low-fat or high-fat diet
• as early as 4 months of age whether fed a low-fat or high-fat diet

adipose tissue
• at 7 months when fed a low-fat diet
• when fed a high fat diet, 7 month old mice exhibit increased adiposity due to an increase in intraabdominal fat depots compared with similarly treated wild-type mice
• when fed a high fat diet due to an increase in intraabdominal fat depots at 7 months of age

liver/biliary system
• at 4 and 7 months in mice fed a high-fat diet
• mild when fed a low-fat diet
• at 7 months in mice fed a high-fat diet

behavior/neurological
• whether fed a low-fat or high-fat diet at 4 and 7 months of age

endocrine/exocrine glands
N
• despite abnormal glucose homeostasis, pancreas morphology is normal whether mice are fed a low-fat or high-fat diet

growth/size/body
• at 4 and 7 months in mice fed a high-fat diet





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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory