Phenotypes associated with this allele
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxp3tm8Ayr mutation
(0 available);
any
Foxp3 mutation
(55 available)
|
|
|
normal phenotype
|
• heterozygous female mice are healthy
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxp3tm8Ayr mutation
(0 available);
any
Foxp3 mutation
(55 available)
|
|
|
mortality/aging
|
• males die by around 4 weeks
|
immune system
|
• male mice develope severe autoimmunity
|