All Phenotypes Fbxo7<tm1a(EUCOMM)Hmgu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Fbxo7^{tm1a(EUCOMM)Hmgu}
targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
MGI:4434927

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fbxo7^{tm1a(EUCOMM)Hmgu}/Fbxo7^{tm1a(EUCOMM)Hmgu}	involves: C57BL/6N	MGI:5317819

Allelic Composition	Fbxo7^{tm1a(EUCOMM)Hmgu}/Fbxo7^{tm1a(EUCOMM)Hmgu}
Genetic Background	involves: C57BL/6N
Cell Lines	HEPD0516_4_G01

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxo7^{tm1a(EUCOMM)Hmgu} mutation (0 available); any Fbxo7 mutation (27 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

increased pro-B cell number ( J:183053 )

• increased percentage of CD43^hiCD25^lo

increased erythroid progenitor cell number ( J:183053 )

• in bone marrow cells

abnormal proerythroblast morphology ( J:183053 )

• increase in early stage pro-erythroblasts (CD71^hiTer119^lo)

decreased erythroblast number ( J:183053 )

immune system

increased pro-B cell number ( J:183053 )

• increased percentage of CD43^hiCD25^lo

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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