Phenotypes associated with this allele

• Allele Symbol: Celf4^{tm1a(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4433345
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Celf4^tm1a(EUCOMM)Wtsi/Celf4^tm1a(EUCOMM)Wtsi	C57BL/6N-Celf4^tm1a(EUCOMM)Wtsi/Wtsi	MGI:5705967
ht2	Celf4^tm1a(EUCOMM)Wtsi/Celf4^+	C57BL/6N-Celf4^tm1a(EUCOMM)Wtsi/Wtsi	MGI:5797433

Genotype
MGI:5705967

hm1

• Allelic Composition: Celf4^{tm1a(EUCOMM)Wtsi}/Celf4^{tm1a(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Celf4^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0372_2_D05

Data Sources

IMPC Data for Celf4

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

absent basilar artery segment ( J:239583 )

DMDD

abnormal vitelline vein topology ( J:239583 )

DMDD

abnormal ductus venosus valve morphology ( J:239583 )

DMDD

dual inferior vena cava ( J:239583 )

DMDD

embryo

abnormal vitelline vein topology ( J:239583 )

DMDD

endocrine/exocrine glands

abnormal bile duct morphology ( J:239583 )

DMDD

growth/size/body

fetal growth retardation ( J:239583 )

DMDD

immune system

blood in lymph vessels ( J:239583 )

DMDD

liver/biliary system

abnormal bile duct morphology ( J:239583 )

DMDD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI

muscle

abnormal eye muscle morphology ( J:239583 )

DMDD

nervous system

absent basilar artery segment ( J:239583 )

DMDD

normal phenotype

no abnormal phenotype detected ( J:239583 )

DMDD

vision/eye

abnormal eye muscle morphology ( J:239583 )

DMDD

Genotype
MGI:5797433

ht2

• Allelic Composition: Celf4^{tm1a(EUCOMM)Wtsi}/Celf4⁺
• Genetic Background: C57BL/6N-Celf4^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0372_2_D05

Data Sources

IMPC Data for Celf4

homeostasis/metabolism

increased circulating insulin level ( J:211773 )

♀

IMPC - WTSI

decreased circulating cholesterol level ( J:211773 )

♂

IMPC - WTSI

decreased circulating calcium level ( J:211773 )

♂

IMPC - WTSI

impaired glucose tolerance ( J:211773 )

♀

IMPC - WTSI