Phenotypes associated with this allele

• Allele Symbol: Cyb561^{tm1a(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4432734
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cyb561^tm1a(EUCOMM)Wtsi/Cyb561^tm1a(EUCOMM)Wtsi	B6JTyr;B6N-Cyb561^tm1a(EUCOMM)Wtsi/Wtsi	MGI:5781602
hm2	Cyb561^tm1a(EUCOMM)Wtsi/Cyb561^tm1a(EUCOMM)Wtsi	Not Specified	MGI:5450098

Genotype
MGI:5781602

hm1

• Allelic Composition: Cyb561^{tm1a(EUCOMM)Wtsi}/Cyb561^{tm1a(EUCOMM)Wtsi}
• Genetic Background: B6JTyr;B6N-Cyb561^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0037_3_G01

Data Sources

IMPC Data for Cyb561

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal behavior ( J:175295 )

♀

IMPC - WTSI

hematopoietic system

increased erythrocyte cell number ( J:175295 )

IMPC - WTSI

increased hematocrit ( J:175295 )

IMPC - WTSI

increased hemoglobin content ( J:175295 )

IMPC - WTSI

homeostasis/metabolism

increased circulating fructosamine level ( J:175295 )

IMPC - WTSI

decreased circulating LDL cholesterol level ( J:175295 )

♂

IMPC - WTSI

increased circulating magnesium level ( J:175295 )

♀

IMPC - WTSI

increased circulating amylase level ( J:175295 )

IMPC - WTSI

integument

abnormal coat/hair pigmentation ( J:175295 )

♂

IMPC - WTSI

pigmentation

abnormal coat/hair pigmentation ( J:175295 )

♂

IMPC - WTSI

Genotype
MGI:5450098

hm2

• Allelic Composition: Cyb561^{tm1a(EUCOMM)Wtsi}/Cyb561^{tm1a(EUCOMM)Wtsi}
• Genetic Background: Not Specified
• Cell Lines: EPD0037_3_G01

Data Sources

IMPC Data for Cyb561

homeostasis/metabolism

decreased circulating calcium level ( J:165965 )

♂

IMPC - HAR

increased circulating iron level ( J:165965 )

♀

IMPC - HAR

decreased circulating serum albumin level ( J:165965 )

IMPC - HAR

decreased circulating total protein level ( J:165965 )

IMPC - HAR

abnormal respiratory quotient ( J:165965 )

IMPC - HAR

behavior/neurological

abnormal response to new environment ( J:165965 )

♂

IMPC - HAR

skeleton

abnormal bone structure ( J:165965 )

IMPC - HAR

abnormal bone mineralization ( J:165965 )

♀

IMPC - HAR

vision/eye

abnormal placement of pupils ( J:165965 )

♀

IMPC - HAR